Saturday, June 5, 2010

The aims of isolating active principles are:

1. Identification of the active ingredient(s).
2. Analysis of the biological effects (pharmacodynamics) of individual ingredients and of their fate in the body (pharmacokinetics).
3. Ensuring a precise and constant dosage in the therapeutic use of chemically pure constituents.
4. The possibility of chemical synthesis, which would afford independence from limited natural supplies and create conditions for the analysis of structure-activity
relationships.

Finally, derivatives of the original constituent may be synthesized in an effort to optimize pharmacological properties. Thus, derivatives of the original constituent
with improved therapeutic usefulness may be developed.

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